Exam Yield

Probability of getting 1 Question from this chapter 109%

You can score up to 4 marks in this Chapter.

Studying this chapter probably yields you easy marks in Pathology too.

Question Pattern

It’s a rather vast chapter (130 pages in Ananthanarayanan )

But the questions have considerable overlap with the Chapter on Immunology in Pathology.

So, not exactly a new chapter to read.

Nevertheless, the questions focus on

  • Basic organisation of the immune system
  • Classical Immune deficiency syndromes
  • Types, examples and mechanism of Hypersensitivity reactions
  • HLA & MHC

Recent Questions

Questions on this chapter from recent NEET and AIIMS examinations have been about
  • Pro-zone phenomenon
  • Types of Organ transplants
  • Adoptive immunity
  • Antigen presenting cells
  • Transplant Rejection Reactions
  • Immunologically privileged sites
  • Wasserman reaction is an example of
  • Interferon – Overview
  • Papain action on immunoglobulin
  • Most potent stimulator of Naive T-cells
  • DiGeorge syndrome – Clinical Features
  • Type II Antibody-Mediated Hypersentivity
  • Classical vs Alternate pathway
  • Nude mice is not resistant to xenograft due
  • MHC molecules – Overview
  • Properties of different immunoglobulins
  • Post-zone phenomenon
  • Molecules produced by Macrophages
  • Hereditary angioneurotic edema
  • MHC class I antigens are found in
  • Hyper IgE syndrome – Clinical features
  • Naegler’s reaction is an example of
  • Active vs Passive Immunity
  • Secretory component of IgA is formed by
  • Double diffusion in two dimensions is called
  • Transplacental Antibody

Suggested Revision

Following areas are good to revise:

  • Functions of Interleukins
  • HLA complex – Overview
  • Functions of T cells
  • Natural Killer cells (NK cells)
  • Hypersensitivity Reactions – Types, Examples & Mechanisms
  • T-cell receptor – Overview
  • Toll-like receptor
  • Pattern-recognition receptors
  • Leucocyte Adhesion Defects
  • Primary immunodeficiency disorders
  • SCID
  • Types of Hypersensitivity
  • Anaphylactic reaction
  • Toxic shock syndrome – Pathophysiology
  • Chemokines – Overview
  • Chronic granulomatous disease
  • Types of immunity
  • Tissue specific Macrophages
  • T cell dependent and Independent antigens

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