Probability of getting 1 Question from this chapter	90%
Ease of Revision	7.81 / 10

It’s a rather vast chapter (130 pages in Ananthanarayanan )

But the questions have considerable overlap with the Chapter on Immunology in Pathology.

So, not exactly a new chapter to read.

Nevertheless, the questions focus on

• Basic organisation of the immune system
• Classical Immune deficiency syndromes
• Types, examples and mechanism of Hypersensitivity reactions
• HLA & MHC

Questions on this chapter from recent NEET and AIIMS examinations have been about

• Pro-zone phenomenon
• Types of Organ transplants
• Adoptive immunity
• Antigen presenting cells
• Transplant Rejection Reactions
• Immunologically privileged sites
• Wasserman reaction is an example of
• Interferon – Overview
• Papain action on immunoglobulin
• Most potent stimulator of Naive T-cells
• DiGeorge syndrome – Clinical Features
• Type II Antibody-Mediated Hypersentivity
• Classical vs Alternate pathway
• Nude mice is not resistant to xenograft due
• MHC molecules – Overview
• Properties of different immunoglobulins
• Post-zone phenomenon
• Molecules produced by Macrophages
• Hereditary angioneurotic edema
• MHC class I antigens are found in
• Hyper IgE syndrome – Clinical features
• Naegler’s reaction is an example of
• Active vs Passive Immunity
• Secretory component of IgA is formed by
• Double diffusion in two dimensions is called
• Transplacental Antibody

Following areas are good to revise:

• Functions of Interleukins
• HLA complex – Overview
• Functions of T cells
• Natural Killer cells (NK cells)
• Hypersensitivity Reactions – Types, Examples & Mechanisms
• T-cell receptor – Overview
• Toll-like receptor
• Pattern-recognition receptors
• Leucocyte Adhesion Defects
• Primary immunodeficiency disorders
• SCID
• Types of Hypersensitivity
• Anaphylactic reaction
• Toxic shock syndrome – Pathophysiology
• Chemokines – Overview
• Chronic granulomatous disease
• Types of immunity
• Tissue specific Macrophages
• T cell dependent and Independent antigens